OTUD3 and EMC1

		OTUD3	EMC1
Description		OTU deubiquitinase 3	ER membrane protein complex subunit 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Endoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Protein-containing Complex EMC Complex
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity	Membrane Insertase Activity
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation Protein K11-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Negative Regulation Of Protein Kinase B Signaling Protein K48-linked Deubiquitination Protein K27-linked Deubiquitination	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Ovarian tumor domain proteases Regulation of PTEN stability and activity
Drugs
Diseases
GWAS		group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 19915572 28067908 20228798 20228799 19122664 23511034)
Interacting Genes		4 interacting genes: HSD17B14 HSPA5 PTEN UBC
Entrez ID		23252	23065
HPRD ID		19417	08306
Ensembl ID		ENSG00000169914	ENSG00000127463
Uniprot IDs		Q5T2D3	Q8N766
PDB IDs		4BOU	6WW7 6Z3W
Enriched GO Terms of Interacting Partners?
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