PHLPP1 and ZCCHC2

Data Source:
BioGRID (affinity chromatography technology)

		PHLPP1	ZCCHC2
Description		PH domain and leucine rich repeat protein phosphatase 1	zinc finger CCHC-type containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle	Cytoplasm
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Nucleic Acid Binding Zinc Ion Binding Phosphatidylinositol Binding
	Biological Process	Regulation Of T Cell Anergy Protein Dephosphorylation Apoptotic Process Signal Transduction Entrainment Of Circadian Clock Regulation Of Apoptotic Process Regulation Of MAPK Cascade Regulation Of JNK Cascade Negative Regulation Of Protein Kinase B Signaling Regulation Of P38MAPK Cascade
Pathways		Negative regulation of the PI3K/AKT network
Drugs
Diseases
GWAS		Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Hip circumference adjusted for BMI ( 28552196) Plateletcrit ( 32888494)	Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Bipolar disorder ( 31043756) Breastfeeding duration ( 25475840) Chronotype ( 30696823) Depressive symptoms x dependent stressful life events interaction (1df test) ( 30718454) Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Menopause (age at onset) ( 29773799) Morning person ( 30696823) Pulse pressure ( 30224653) Serum albumin level ( 23022100)
Interacting Genes		6 interacting genes: BRAP CSNK1A1 GSK3B SLC9A3R1 SUGT1 WDR48
Entrez ID		23239	54877
HPRD ID		15145	11696
Ensembl ID		ENSG00000081913	ENSG00000141664
Uniprot IDs		O60346	Q9BRD4 Q9C0B9
PDB IDs
Enriched GO Terms of Interacting Partners?
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