PLXND1 and PODXL2

Data Source:
BioGRID (affinity chromatography technology)

		PLXND1	PODXL2
Description		plexin D1	podocalyxin like 2
Image			No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane Lamellipodium Lamellipodium Membrane	Golgi Lumen Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Semaphorin Receptor Activity Protein Domain Specific Binding	Protein Binding Glycosaminoglycan Binding
	Biological Process	Angiogenesis Branching Involved In Blood Vessel Morphogenesis Kidney Development Outflow Tract Morphogenesis Cardiac Septum Development Negative Regulation Of Cell Adhesion Positive Regulation Of Transcription Of Notch Receptor Target Synapse Assembly Regulation Of Cell Shape Regulation Of Cell Migration Positive Regulation Of Protein Binding Aorta Development Regulation Of GTPase Activity Endothelial Cell Migration Regulation Of Angiogenesis Positive Regulation Of Axonogenesis Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Coronary Vasculature Development Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance	Leukocyte Tethering Or Rolling
Pathways		Other semaphorin interactions NOTCH3 Intracellular Domain Regulates Transcription	Cytosolic sulfonation of small molecules
Drugs
Diseases
GWAS		Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 25673412) Low density lipoprotein cholesterol levels ( 32154731) Mean platelet volume ( 32888494) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)	Refractive error ( 32231278)
Interacting Genes		3 interacting genes: HOXB5 MACF1 SEMA4A	1 interacting genes: SELL
Entrez ID		23129	50512
HPRD ID		05046	15154
Ensembl ID		ENSG00000004399	ENSG00000114631
Uniprot IDs		Q9Y4D7	Q9NZ53
PDB IDs		3H6N
Enriched GO Terms of Interacting Partners?
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