MYCBP2 and FBXL3

Data Source:
BioGRID (biochemical)

		MYCBP2	FBXL3
Description		MYC binding protein 2	F-box and leucine rich repeat protein 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Membrane Axon Intracellular Membrane-bounded Organelle	Ubiquitin Ligase Complex Nucleus Cytosol Nuclear Body SCF Ubiquitin Ligase Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Neuromuscular Process Regulation Of Cytoskeleton Organization Regulation Of Axon Guidance	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Destabilization Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Post-translational Protein Modification Rhythmic Process Regulation Of Cell Cycle
Pathways			Association of TriC/CCT with target proteins during biosynthesis Circadian Clock Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Chronotype ( 30696823) Metabolite levels ( 23823483) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		15 interacting genes: APPL1 ATP13A2 CALM1 ERBB3 FBXO45 MYC NMNAT2 PTPN12 SRPK2 TTN UBE2D2 UBE2D3 UBE2L3 YWHAG YWHAQ	7 interacting genes: CDC34 CEP57 CRY1 MSRA PICK1 SKP1 UBE2D2
Entrez ID		23077	26224
HPRD ID		10104	05737
Ensembl ID		ENSG00000005810	ENSG00000005812
Uniprot IDs		O75592	Q9UKT7
PDB IDs		5O6C 6T7F	4I6J
Enriched GO Terms of Interacting Partners?
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