STK38L and MX2

Data Source:
BioGRID (proximity labelling technology)

		STK38L	MX2
Description		serine/threonine kinase 38 like	MX dynamin like GTPase 2
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Actin Cytoskeleton Membrane	Nucleus Nuclear Pore Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Mitochondrial Membrane Dendritic Spine Head Presynapse Postsynaptic Endocytic Zone Membrane
	Molecular Function	Magnesium Ion Binding Actin Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	GTPase Activity Protein Binding GTP Binding Microtubule Binding
	Biological Process	Protein Phosphorylation Peptidyl-serine Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Component Organization	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Defense Response Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Response To Interferon-alpha Regulation Of Nucleocytoplasmic Transport Regulation Of Synapse Structure Or Activity MRNA Transport Defense Response To Virus Regulation Of Cell Cycle Type I Interferon Signaling Pathway Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization
Pathways			ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs		Fostamatinib
Diseases
GWAS		Diastolic blood pressure ( 30224653) Glioma ( 30714141) Mean platelet volume ( 32888494)	Cutaneous malignant melanoma ( 32341527) Melanoma ( 21983787 28212542) Nevus count or cutaneous melanoma ( 32341527 30429480) Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		3 interacting genes: MOB2 STK24 YWHAB	3 interacting genes: ATRIP EHMT2 PIAS2
Entrez ID		23012	4600
HPRD ID		10256	01001
Ensembl ID		ENSG00000211455	ENSG00000183486
Uniprot IDs		Q9Y2H1	P20592
PDB IDs		5XQZ	4WHJ 4X0R 5UOT
Enriched GO Terms of Interacting Partners?
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