OIT3 and UNC5B

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		OIT3	UNC5B
Description		oncoprotein induced transcript 3	unc-5 netrin receptor B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nuclear Envelope Cell Surface	Plasma Membrane Integral Component Of Membrane Membrane Raft
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding	Netrin Receptor Activity Protein Binding
	Biological Process	Urate Homeostasis	Angiogenesis Apoptotic Process Axon Guidance Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Anterior/posterior Axon Guidance Netrin-activated Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways			Netrin-1 signaling Netrin mediated repulsion signals Caspase activation via Dependence Receptors in the absence of ligand
Drugs
Diseases
GWAS		Coronary artery disease ( 33020668) Low density lipoprotein cholesterol levels ( 29403010) Refractive error ( 32231278) Total cholesterol levels ( 29403010)	Attention deficit hyperactivity disorder ( 18839057) Chronotype ( 30696823) Diisocyanate-induced asthma ( 25918132) Problematic alcohol use ( 32451486) Vitiligo ( 22951725)
Interacting Genes		9 interacting genes: CRCT1 FBXO34 HOXA1 KRTAP11-1 LCE1C LCE1F LCE3A MEOX2 VAC14	3 interacting genes: DAPK1 PPP2R1B TREM2
Entrez ID		170392	219699
HPRD ID		17660	08487
Ensembl ID		ENSG00000138315	ENSG00000107731
Uniprot IDs		Q8WWZ8	Q8IZJ1
PDB IDs
Enriched GO Terms of Interacting Partners?
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