IDO2 and NKX6-3

Data Source:
BioGRID (affinity chromatography technology)

		IDO2	NKX6-3
Description		indoleamine 2,3-dioxygenase 2	NK6 homeobox 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Chromatin Nucleus
	Molecular Function	Tryptophan 2,3-dioxygenase Activity Heme Binding Indoleamine 2,3-dioxygenase Activity Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Immune System Process Tryptophan Catabolic Process Tryptophan Catabolic Process To Kynurenine 'de Novo' NAD Biosynthetic Process From Tryptophan	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Determination Glandular Epithelial Cell Differentiation Regulation Of Transcription By RNA Polymerase II Cell Differentiation Negative Regulation Of Epithelial Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Tryptophan catabolism
Drugs
Diseases
GWAS			Birth weight ( 31043758) Red cell distribution width ( 28957414) Type 2 diabetes ( 32499647)
Interacting Genes		2 interacting genes: BANP LZTS1
Entrez ID		169355	157848
HPRD ID		14113	08053
Ensembl ID		ENSG00000188676	ENSG00000165066
Uniprot IDs		Q6ZQW0	A6NJ46
PDB IDs
Enriched GO Terms of Interacting Partners?
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