NKX6-3 and IDO2

Data Source:
BioGRID (affinity chromatography technology)

		NKX6-3	IDO2
Description		NK6 homeobox 3	indoleamine 2,3-dioxygenase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Tryptophan 2,3-dioxygenase Activity Heme Binding Indoleamine 2,3-dioxygenase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Determination Glandular Epithelial Cell Differentiation Regulation Of Transcription By RNA Polymerase II Cell Differentiation Negative Regulation Of Epithelial Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Immune System Process Tryptophan Catabolic Process Tryptophan Catabolic Process To Kynurenine 'de Novo' NAD Biosynthetic Process From Tryptophan
Pathways			Tryptophan catabolism
Drugs
Diseases
GWAS		Birth weight ( 31043758) Red cell distribution width ( 28957414) Type 2 diabetes ( 32499647)
Interacting Genes			2 interacting genes: BANP LZTS1
Entrez ID		157848	169355
HPRD ID		08053	14113
Ensembl ID		ENSG00000165066	ENSG00000188676
Uniprot IDs		A6NJ46	Q6ZQW0
PDB IDs
Enriched GO Terms of Interacting Partners?
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