ZNF785 and TMEM219

Data Source:
BioGRID (proximity labelling technology)

		ZNF785	TMEM219
Description		zinc finger protein 785	transmembrane protein 219
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Apoptotic Process Regulation Of Apoptotic Process
Pathways		Generic Transcription Pathway	TP53 Regulates Transcription of Death Receptors and Ligands
Drugs
Diseases
GWAS		Eosinophil counts ( 27863252)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		22 interacting genes: CABP2 CBY2 CCDC136 CCNDBP1 CEP70 EHMT2 GOLGA6L9 HOOK1 KIFC3 KRT36 KRTAP10-1 KRTAP10-5 KRTAP12-2 MDFI MID2 MTUS2 PNMA2 PRR7 STX1A STX2 TPM2 TRIP6
Entrez ID		146540	124446
HPRD ID		08120	18546
Ensembl ID		ENSG00000197162	ENSG00000149932
Uniprot IDs		A0A024QZC7 A8K8V0	A0A024R618 Q86XT9
PDB IDs
Enriched GO Terms of Interacting Partners?
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