CPNE8 and ANO6

Data Source:
BioGRID (affinity chromatography technology)

		CPNE8	ANO6
Description		copine 8	anoctamin 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Extracellular Exosome	Cytosol Plasma Membrane Cell Surface Membrane Chloride Channel Complex Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Molecular_function Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding	Calcium Activated Cation Channel Activity Intracellular Calcium Activated Chloride Channel Activity Voltage-gated Ion Channel Activity Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding Phospholipid Scramblase Activity Metal Ion Binding Protein Dimerization Activity
	Biological Process	Biological_process Cellular Response To Calcium Ion	Dendritic Cell Chemotaxis Activation Of Blood Coagulation Via Clotting Cascade Cation Transport Chloride Transport Blood Coagulation Plasma Membrane Phospholipid Scrambling Positive Regulation Of Bone Mineralization Bleb Assembly Ion Transmembrane Transport Positive Regulation Of Ion Transmembrane Transport Purinergic Nucleotide Receptor Signaling Pathway Sodium Ion Transmembrane Transport Positive Regulation Of Apoptotic Process Neutrophil Degranulation Negative Regulation Of Cell Volume Pore Complex Assembly Transmembrane Transport Positive Regulation Of Phagocytosis, Engulfment Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Calcium Ion Transmembrane Transport Positive Regulation Of Monocyte Chemotaxis Phosphatidylserine Exposure On Blood Platelet Chloride Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways			Stimuli-sensing channels Neutrophil degranulation
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Arterial stiffness index ( 31235810) Bipolar disorder ( 28115744) Bisphosphonate-associated atypical femoral fracture ( 31006051) Bitter alcoholic beverage consumption ( 31046077) Body mass index ( 25673413) Body size at age 10 ( 32376654) Chronotype ( 30696823) Heart rate ( 23583979) Heart rate response to recovery post exercise ( 29769521) Irritable bowel syndrome ( 29626450) Morning person ( 30696823) Resting heart rate ( 29769521)	Ankylosing spondylitis ( 22138694) Insomnia ( 29520036) Urate levels in obese individuals ( 25811787) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		2 interacting genes: NECAB1 SORBS3
Entrez ID		144402	196527
HPRD ID		16747	18746
Ensembl ID		ENSG00000139117	ENSG00000177119
Uniprot IDs		Q86YQ8	B3KX12 Q4KMQ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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