SLC34A3 and USP16

Data Source:
HPRD (in vivo)

		SLC34A3	USP16
Description		solute carrier family 34 member 3	ubiquitin specific peptidase 16
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Brush Border Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane Vesicle	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Sodium:phosphate Symporter Activity Protein Binding	Transcription Coactivator Activity Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Zinc Ion Binding Histone Binding Ubiquitin Binding
	Biological Process	Sodium Ion Transport Phosphate Ion Transport Cellular Phosphate Ion Homeostasis Sodium Ion Transmembrane Transport Sodium-dependent Phosphate Transport	Mitotic Cell Cycle Regulation Of Transcription By RNA Polymerase II Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Histone Deubiquitination Protein Deubiquitination Protein Phosphopantetheinylation Monoubiquitinated Histone H2A Deubiquitination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Elongation Positive Regulation Of Transcription By RNA Polymerase II Protein Homotetramerization Cell Division Regulation Of Cell Cycle Histone H2A K63-linked Deubiquitination Mitotic Nuclear Division
Pathways		Type II Na+/Pi cotransporters Defective SLC34A3 causes Hereditary hypophosphatemic rickets with hypercalciuria (HHRH)	Ub-specific processing proteases
Drugs
Diseases		Hypophosphatemic rickets; X-Linked dominant hypophosphatemia (XLH); Autosomal dominant hypophosphatemic rickets (ADHR); Autosomal recessive hypophosphatemic rickets (ARHR); Hereditary hypophophatemic rickets with hypercalciuria (HHRH)
GWAS
Interacting Genes		4 interacting genes: CLRN1 GPX8 TMEM167B TMEM234	15 interacting genes: CALM1 CDK1 EXOSC10 FBXO11 H2AC18 H2AC20 H2AC4 H2AZ1 H2BC3 H4-16 PLK1 PTOV1 TTK UBC UBD
Entrez ID		142680	10600
HPRD ID		10236	06881
Ensembl ID		ENSG00000198569	ENSG00000156256
Uniprot IDs		Q8N130	Q9Y5T5
PDB IDs			2I50
Enriched GO Terms of Interacting Partners?
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