CRYBA1 and FBXO3

Data Source:
BioGRID (genetic interference)

		CRYBA1	FBXO3
Description		crystallin beta A1	F-box protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytosol
	Molecular Function	Molecular_function Structural Constituent Of Eye Lens Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Negative Regulation Of Cytokine Production Lens Development In Camera-type Eye Visual Perception Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Anoikis	Proteolysis Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mean reticulocyte volume ( 32888494) Night sleep phenotypes ( 27126917)	Chronotype ( 30696823) Coronary artery calcification ( 23870195) Fruit consumption ( 32066663) Morning person ( 30696823)
Interacting Genes		24 interacting genes: ARID5A BANF2 CELF6 CERK CHCHD2 CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 CYSRT1 FOXH1 HOXC8 KRTAP11-1 KRTAP13-2 KRTAP13-3 LASP1 NOXA1 PLEKHF2 PROP1 RBPMS RHOXF2 VAC14 YPEL3	2 interacting genes: SKP1 SMURF1
Entrez ID		1411	26273
HPRD ID		00429	16433
Ensembl ID		ENSG00000108255	ENSG00000110429
Uniprot IDs		P05813	Q49AF1 Q9UK99
PDB IDs			5HDW
Enriched GO Terms of Interacting Partners?
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