CRY2 and TNFRSF9

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		CRY2	TNFRSF9
Description		cryptochrome circadian regulator 2	TNF receptor superfamily member 9
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Nuclear Speck	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding DNA Binding Damaged DNA Binding Single-stranded DNA Binding Deoxyribodipyrimidine Photo-lyase Activity DNA (6-4) Photolyase Activity Protein Binding Blue Light Photoreceptor Activity Phosphatase Binding FAD Binding	Protein Binding Cytokine Binding Signaling Receptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Photoreactive Repair Circadian Rhythm Response To Light Stimulus Blue Light Signaling Pathway Response To Activity Protein-chromophore Linkage Negative Regulation Of Phosphoprotein Phosphatase Activity Circadian Regulation Of Gene Expression Glucose Homeostasis Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transcription, DNA-templated Regulation Of Sodium-dependent Phosphate Transport Negative Regulation Of Glucocorticoid Receptor Signaling Pathway	Apoptotic Process Negative Regulation Of Cell Population Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Cell Population Proliferation
Pathways		Circadian Clock	TNFs bind their physiological receptors
Drugs			Urelumab
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Axial length ( 24144296) Fasting blood glucose ( 20081858 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Glycemic traits (pleiotropy) ( 31021400) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969) Visceral fat ( 22589738)	Blond vs. brown/black hair color ( 30531825) Celiac disease ( 20190752) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Psoriasis ( 25903422 23143594) Rheumatoid arthritis ( 30423114 24390342) Ulcerative colitis ( 28067908 21297633) Waist-hip ratio ( 28552196)
Interacting Genes		50 interacting genes: ATXN1 BHLHE41 BRCA1 CLOCK CTBP1 CYSRT1 DELEC1 EZH2 KLHL6 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP19-6 KRTAP4-2 KRTAP5-1 KRTAP5-2 KRTAP5-4 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-8 LMNA MID1 MTUS2 NADK NBPF19 NOTCH2NLA NPAS2 PDE9A PER1 PER2 PER3 PICK1 PPP2R1B PPP2R5D PPP2R5E PPP5C PTGER4 SBK3 SDCBP2 STK11 TIMELESS TRAF1 TRAF2 TTC1 VWC2 XRN2 ZBTB42	7 interacting genes: LRR1 SERP1 TNFRSF4 TNFSF9 TRAF1 TRAF2 TRAF3
Entrez ID		1408	3604
HPRD ID		07226	03767
Ensembl ID		ENSG00000121671	ENSG00000049249
Uniprot IDs		A0A0D2X7Z3 A2I2P1 Q49AN0	Q07011
PDB IDs			6A3V 6A3W 6BWV 6CPR 6CU0 6MGP 6MHR 6MI2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?