MAP3K8 and ADAM10

  • Data Source:
  • BioGRID (two hybrid)

MAP3K8

ADAM10

Description mitogen-activated protein kinase kinase kinase 8 ADAM metallopeptidase domain 10
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 30820047)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Apolipoprotein A1 levels ( 32203549)
  • Chronotype ( 30696823)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Family history of Alzheimer's disease ( 30617256)
  • Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355)
  • Metabolite levels ( 23823483)
  • Schizophrenia ( 30285260)
Interacting Genes 17 interacting genes: ACY3 AKT1 BMPR2 CD40 CHUK MAP2K1 MAP2K4 MAP3K14 NFKB1 NFKB2 REL RELA RIPK1 STIP1 TNIP2 TRAF2 TRAF6 7 interacting genes: AXL DLL1 EFNA1 EFNA2 EPHA3 SH3D19 TGFA
Entrez ID 1326 102
HPRD ID 01863 03723
Ensembl ID ENSG00000107968 ENSG00000137845
Uniprot IDs P41279 Q6FG25 A0A024R5U5 O14672
PDB IDs 4Y83 4Y85 5IU2 1M1I 6BDZ 6BE6
Enriched GO Terms of Interacting Partners?
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