COL15A1 and GAS1

Data Source:
BioGRID (genetic interference)

		COL15A1	GAS1
Description		collagen type XV alpha 1 chain	growth arrest specific 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type XV Trimer Extracellular Space Endoplasmic Reticulum Lumen Integral Component Of Membrane Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Exosome	Plasma Membrane Integral Component Of Membrane Anchored Component Of Plasma Membrane
	Molecular Function	Extracellular Matrix Structural Constituent Extracellular Matrix Structural Constituent Conferring Tensile Strength	Protein Binding
	Biological Process	Angiogenesis Endothelial Cell Morphogenesis Cell Adhesion Signal Transduction Extracellular Matrix Organization Collagen Catabolic Process	Cell Cycle Arrest Regulation Of Smoothened Signaling Pathway Negative Regulation Of Protein Processing Cellular Response To Vascular Endothelial Growth Factor Stimulus Regulation Of Apoptotic Process Cell Fate Commitment Negative Regulation Of Mitotic Cell Cycle Developmental Growth Regulation Of ER To Golgi Vesicle-mediated Transport
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Collagen chain trimerization	Ligand-receptor interactions Activation of SMO
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Asthma ( 31959851 32296059) Blood protein levels ( 30072576 29875488) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease ( 30804561) Epithelial ovarian cancer ( 25134534) Fractures (paediatric) ( 32742401) Gut microbiota alpha diversity (Shannon index) ( 33208821) Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales) ( 33208821) Height ( 28552196) Lateral ventricle temporal horn volume ( 31530798) Pulse pressure ( 30224653 30578418)	Blood protein levels ( 30072576) Borderline personality disorder ( 28632202) Heel bone mineral density ( 30598549) Insulin resistance/response ( 21901158) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes			4 interacting genes: BIRC2 DLK1 ERRFI1 SHH
Entrez ID		1306	2619
HPRD ID		00380	00747
Ensembl ID		ENSG00000204291	ENSG00000180447
Uniprot IDs		B3KTP7 P39059	P54826
PDB IDs		3N3F
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?