ALKBH2 and NDFIP2

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ALKBH2	NDFIP2
Description		alkB homolog 2, alpha-ketoglutarate dependent dioxygenase	Nedd4 family interacting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Golgi Membrane Cytoplasm Mitochondrion Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane Multivesicular Body Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Ferrous Iron Binding DNA-N1-methyladenine Dioxygenase Activity Cytosine C-5 DNA Demethylase Activity 1-ethyladenine Demethylase Activity	Protein Binding WW Domain Binding
	Biological Process	DNA Dealkylation Involved In DNA Repair Oxidative DNA Demethylation Oxidative Demethylation DNA Demethylation	Ubiquitin-dependent Protein Catabolic Process Vacuolar Transport Negative Regulation Of Gene Expression Metal Ion Transport Positive Regulation Of Protein Ubiquitination Negative Regulation Of Transporter Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Protein Transport
Pathways		ALKBH2 mediated reversal of alkylation damage
Drugs		Ascorbic acid
Diseases
GWAS			Leisure-time exercise behaviour (age-stratified) ( 30102679) Major depressive disorder ( 23377640) Metabolite levels ( 23823483) Pancreatic cancer ( 20686608) Smoking status (ever vs never smokers) ( 30643258) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		1 interacting genes: GOLGA2	8 interacting genes: AQP2 ITCH LYN NEDD4 NEDD4L SMURF1 UQCRH WWP2
Entrez ID		121642	54602
HPRD ID		14712	17629
Ensembl ID		ENSG00000189046	ENSG00000102471
Uniprot IDs		Q6NS38	B4DGY6 Q9NV92
PDB IDs		3BTX 3BTY 3BTZ 3BU0 3BUC 3H8O 3H8R 3H8X 3RZG 3RZH 3RZJ 3RZK 3RZL 3RZM 3S57 3S5A 4MG2 4MGT
Enriched GO Terms of Interacting Partners?
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