SLC7A9 and PUM3

Data Source:
BioGRID (affinity chromatography technology)

		SLC7A9	PUM3
Description		solute carrier family 7 member 9	pumilio RNA binding family member 3
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Brush Border Membrane	Nucleoplasm Chromosome Nucleolus Endoplasmic Reticulum
	Molecular Function	Protein Binding Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-cystine Transmembrane Transporter Activity Peptide Antigen Binding	DNA Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Amino Acid Transmembrane Transport Amino Acid Transport Neutral Amino Acid Transport L-cystine Transport Leukocyte Migration Protein-containing Complex Assembly L-alpha-amino Acid Transmembrane Transport	Regulation Of Translation Regulation Of Protein ADP-ribosylation
Pathways		Basigin interactions Amino acid transport across the plasma membrane Defective SLC3A1 causes cystinuria (CSNU) Defective SLC7A9 causes cystinuria (CSNU)
Drugs
Diseases		Cystinuria
GWAS		Blood metabolite levels ( 24816252) Chronic kidney disease ( 20383146) Creatinine levels ( 31015462 29403010 20383145) Estimated glomerular filtration rate ( 31015462 30604766) Fractional excretion of metabolites in chronic kidney disease ( 29545352) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Urate levels ( 31578528) Urinary metabolite levels in chronic kidney disease ( 29545352 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolites ( 21572414) Urinary metabolites (H-NMR features) ( 24586186)	Depression ( 29700475) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		3 interacting genes: CREB3 HSPB1 TGM2	4 interacting genes: APP CALM1 HPS6 ITGB1BP2
Entrez ID		11136	9933
HPRD ID		04997	08822
Ensembl ID		ENSG00000021488	ENSG00000080608
Uniprot IDs		P82251	Q15397
PDB IDs		6LI9 6LID	4WZR 4WZW
Enriched GO Terms of Interacting Partners?
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