CKAP4 and RIC8B

Data Source:
BioGRID (pull down)

		CKAP4	RIC8B
Description		cytoskeleton associated protein 4	RIC8 guanine nucleotide exchange factor B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Lipid Droplet Cytosol Cytoskeleton Plasma Membrane Membrane Integral Component Of Membrane Nuclear Speck Azurophil Granule Membrane Specific Granule Membrane Cytoplasmic Ribonucleoprotein Granule Lamellar Body Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Cytosol Plasma Membrane Cell Cortex
	Molecular Function	RNA Binding	G-protein Alpha-subunit Binding Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity
	Biological Process	Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Surfactant metabolism Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Metabolite levels ( 23823483) Refractive error ( 32231278)	Adiponectin levels ( 31178129) Brain morphology (MOSTest) ( 32665545) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Height ( 31562340) Night sleep phenotypes ( 27126917) PR interval ( 32439900) Severe influenza A (H1N1) infection ( 26379185) Social autistic-like traits ( 24133439) Triglyceride levels ( 29083408 32203549 28334899 32154731) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		13 interacting genes: ASCC2 ATF4 DKK1 HAMP LINC01554 MLH1 MVP NDUFB7 NKX3-1 PLAT THOC7 TSNAX WASHC3	3 interacting genes: GNAQ GNAS LRP1
Entrez ID		10970	55188
HPRD ID		16717	16452
Ensembl ID		ENSG00000136026	ENSG00000111785
Uniprot IDs		A0A024RBH2 Q07065	A0A024RBG9 B7WPL0 Q9NVN3
PDB IDs
Enriched GO Terms of Interacting Partners?
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