ADCY2 and OBP2A

Data Source:
HPRD (in vitro)

		ADCY2	OBP2A
Description		adenylate cyclase 2	odorant binding protein 2A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Dendrite Membrane Raft	Cellular_component Extracellular Space
	Molecular Function	Magnesium Ion Binding Adenylate Cyclase Activity ATP Binding Adenylate Cyclase Binding Manganese Ion Binding	Odorant Binding Small Molecule Binding
	Biological Process	Renal Water Homeostasis CAMP Biosynthetic Process G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway CAMP-mediated Signaling Activation Of Protein Kinase A Activity Cellular Response To Glucagon Stimulus Cellular Response To Forskolin	Sensory Perception Of Chemical Stimulus Sensory Perception Of Smell Response To Stimulus
Pathways		Glucagon signaling in metabolic regulation PKA activation PKA activation in glucagon signalling Adenylate cyclase activating pathway Adenylate cyclase inhibitory pathway Adenylate cyclase inhibitory pathway G alpha (s) signalling events G alpha (s) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events Vasopressin regulates renal water homeostasis via Aquaporins Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis
Drugs		Colforsin 2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE Aurothioglucose	Tretinoin
Diseases
GWAS		Anxiety and stress-related disorders ( 31116379) Atorvastatin-induced myopathy ( 31220337) Bipolar disorder ( 24618891 31043756) Bipolar disorder (age of onset <21) or attention deficit hyperactivity disorder ( 27890468) Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Bipolar I disorder ( 31043756) Capecitabine sensitivity ( 22864933) Coffee consumption ( 31046077) Cognitive decline rate in late mild cognitive impairment ( 26252872) Food addiction ( 27106561) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Oropharynx cancer ( 27749845) Pars opercularis volume ( 31530798) Plasma factor VII activating protease levels ( 30070759) Posterior-cingulate cortex volume ( 31530798) Smoking status (heavy vs never) ( 26423011) Visceral fat ( 22589738)	Coagulation factor levels ( 23267103) Subcutaneous adipose tissue ( 29178545) Subcutaneous adipose tissue (sex interaction) ( 29178545)
Interacting Genes		6 interacting genes: ADCY1 ADCY5 DRD4 F2RL1 GNAS GNG2	2 interacting genes: ADRB2 OR1G1
Entrez ID		108	29991
HPRD ID		00052	01253
Ensembl ID		ENSG00000078295	ENSG00000122136
Uniprot IDs		Q08462 Q71UM8	B7ZLH4 Q5T8A4 Q5T8A5 Q9NY56
PDB IDs			4RUN
Enriched GO Terms of Interacting Partners?
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