CFL2 and ZYG11B

		CFL2	ZYG11B
Description		cofilin 2	zyg-11 family member B, cell cycle regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Actin Cytoskeleton Nuclear Matrix Z Disc I Band Extracellular Exosome	Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Actin Filament Binding	Protein Binding
	Biological Process	Skeletal Muscle Tissue Development Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Sarcomere Organization Muscle Cell Cellular Homeostasis Cell Motility Actin Filament Severing	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases		Nemaline myopathy
GWAS		Atrial fibrillation ( 30061737 29892015) Hip circumference adjusted for BMI ( 28552196)	Monocyte percentage of white cells ( 32888494)
Interacting Genes		13 interacting genes: ACTB ACTG1 CAP2 CFL1 DSTN LIMK1 POT1 RAB2A RNF4 SSH1 STK11 TRIM7 UBE2I	4 interacting genes: CUL2 ELOB ELOC GBF1
Entrez ID		1073	79699
HPRD ID		03262	13356
Ensembl ID		ENSG00000165410	ENSG00000162378
Uniprot IDs		Q549N0 Q9Y281	A8DPD7 B4DK95 Q9C0D3
PDB IDs
Enriched GO Terms of Interacting Partners?
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