SPEG and PNKD

Data Source:
BioGRID (biochemical)

		SPEG	PNKD
Description		striated muscle enriched protein kinase	PNKD metallo-beta-lactamase domain containing
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Mitochondrion Membrane
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Hydroxyacylglutathione Hydrolase Activity Protein Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Muscle Organ Development Negative Regulation Of Cell Population Proliferation Muscle Cell Differentiation	Methylglyoxal Catabolic Process To D-lactate Via S-lactoyl-glutathione Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Dopamine Metabolic Process Negative Regulation Of Neurotransmitter Secretion Neuromuscular Process Controlling Posture
Pathways
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163) Resting heart rate ( 29769521 27798624)	Colorectal cancer ( 28960316) Colorectal cancer or advanced adenoma ( 30510241) Granulocyte count ( 27863252) Height ( 28552196) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 28067908 23128233) Monocyte count ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Plateletcrit ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systolic blood pressure ( 30578418) Triglyceride levels ( 32203549) White blood cell count ( 27863252)
Interacting Genes		5 interacting genes: APP HSF2BP MEOX2 PICK1 PRMT1	5 interacting genes: APP ENO3 KCTD9 MAGEA11 MYL12B
Entrez ID		10290	25953
HPRD ID		10653	11369
Ensembl ID		ENSG00000072195	ENSG00000127838
Uniprot IDs		Q15772	A0A024R415 Q8N490
PDB IDs		1U2H
Enriched GO Terms of Interacting Partners?
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