STAG1 and SMC1B

Data Source:
BioGRID (biochemical)

		STAG1	SMC1B
Description		stromal antigen 1	structural maintenance of chromosomes 1B
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol Cohesin Complex Nuclear Matrix Nuclear Body Mitotic Spindle Pole	Chromosome, Centromeric Region Lateral Element Nucleus Nucleoplasm Cytosol Cohesin Complex Meiotic Cohesin Complex Nuclear Meiotic Cohesin Complex
	Molecular Function	Chromatin Binding Protein Binding	DNA Binding ATP Binding
	Biological Process	Sister Chromatid Cohesion Cell Division Mitotic Spindle Assembly	Sister Chromatid Cohesion Mitotic Sister Chromatid Cohesion Meiotic Cell Cycle
Pathways		Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression	Meiotic synapsis
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Apolipoprotein B levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 28892062 25673413) C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Central corneal thickness ( 32528159 31798171 29760442) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 29212778 30104761) Dentures ( 31235808) General risk tolerance (MTAG) ( 30643258) HDL cholesterol ( 30275531) Height ( 25282103) Intraocular pressure ( 29617998) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Multisite chronic pain ( 31194737) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Plateletcrit ( 32888494) Schizophrenia ( 28991256 25056061 29483656 30285260)	Height ( 28552196) Peanut allergy (maternal genetic effects) ( 29489655)
Interacting Genes		6 interacting genes: CALM1 RAD21 SMAD2 SMAD9 STAG2 WFDC5	1 interacting genes: SMC3
Entrez ID		10274	27127
HPRD ID		05076	10564
Ensembl ID		ENSG00000118007	ENSG00000077935
Uniprot IDs		Q4LE48 Q8WVM7	Q8NDV3
PDB IDs		5QSM 5QSN 5QSO 5QSP 5QSQ 5QSR 5QSS 5QST 5QSU 5QSV 5QSW 5QSX 5QSY 5QSZ 6QB5 6R7O 6RRC 6RRK 6WG3
Enriched GO Terms of Interacting Partners?
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