MPHOSPH9 and RAB35

Data Source:
BioGRID (proximity labelling technology)

		MPHOSPH9	RAB35
Description		M-phase phosphoprotein 9	RAB35, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Centriole Membrane	Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Clathrin-coated Vesicle Membrane Cell Projection Membrane Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function		GTPase Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding GDP Binding
	Biological Process		Mitotic Cytokinesis Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus
Pathways			TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Educational attainment ( 25201988) Intelligence (MTAG) ( 29326435) Multiple sclerosis ( 19525953) Plasma anti-thyroglobulin levels ( 29678681) Platelet count ( 32888494 27863252) Plateletcrit ( 27863252) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Tourette syndrome ( 30818990) Type 2 diabetes ( 24509480 30297969 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382) Venous thromboembolism ( 31420334)	Heel bone mineral density ( 30598549)
Interacting Genes		3 interacting genes: SVIL YWHAG YWHAZ	9 interacting genes: APP CALCOCO2 CBR3 GNPAT IDH3B PTPRS TBPL1 TRIM54 WDCP
Entrez ID		10198	11021
HPRD ID		12022	05010
Ensembl ID		ENSG00000051825	ENSG00000111737
Uniprot IDs		Q99550	Q15286
PDB IDs			3TW8 6EKK 6IF2 6IF3
Enriched GO Terms of Interacting Partners?
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