CDH6 and DNAH5

Data Source:
BioGRID (pull down)

		CDH6	DNAH5
Description		cadherin 6	dynein axonemal heavy chain 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Adherens Junction Integral Component Of Membrane Catenin Complex Cell Junction	Extracellular Region Cytoplasm Microtubule Axoneme Dynein Complex Motile Cilium Outer Dynein Arm 9+2 Motile Cilium
	Molecular Function	Calcium Ion Binding Cadherin Binding	ATP Binding ATP-dependent Microtubule Motor Activity, Minus-end-directed Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Notch Signaling Pathway Multicellular Organism Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules	Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Microtubule-based Movement Determination Of Left/right Symmetry Heart Development Lateral Ventricle Development Flagellated Sperm Motility Outer Dynein Arm Assembly Establishment Of Localization In Cell Cilium Assembly
Pathways		Adherens junctions interactions
Drugs
Diseases			Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome
GWAS		Adventurousness ( 30643258) Cocaine dependence ( 31212010) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Emphysema-related traits ( 20709820) Gamma glutamyl transferase levels ( 29403010) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549 28869591) Late-onset myasthenia gravis ( 26562150) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Response to lamotrigine and valproic acid in genetic generalized epilepsy ( 32308125) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Resting heart rate ( 27798624) Rheumatoid arthritis ( 28118524) Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) ( 28118524) Smoking status (ever vs never smokers) ( 30643258) Sweet taste preference ( 32572145)	Antidepressant treatment resistance (number of drugs prescribed) ( 30700811) Coffee consumption ( 29367735) Corneal astigmatism ( 23322567) Emphysema imaging phenotypes ( 26030696) Gut microbiota relative abundance (unclassified genus belonging to family Ruminococcaceae) ( 33208821) IgE grass sensitization ( 22036096) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) Subclinical atherosclerosis traits (other) ( 17903303) Thyroid volume in Hashimotoâ€™s thyroiditis ( 32019955) Toxicity response to radiotherapy in prostate cancer (decreased urine stream) (time to event) ( 27515689) Visceral fat ( 22589738)
Interacting Genes		5 interacting genes: CDH10 CDH18 CDH19 CDH7 CDH9	1 interacting genes: MTDH
Entrez ID		1004	1767
HPRD ID		04305	04514
Ensembl ID		ENSG00000113361	ENSG00000039139
Uniprot IDs		P55285	Q8TE73
PDB IDs		5VEB
Enriched GO Terms of Interacting Partners?
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