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AKAP12
Description
A-kinase anchoring protein 12
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Focal Adhesion
Cell Cortex
Neuronal Cell Body
Schaffer Collateral - CA1 Synapse
Molecular Function
Protein Binding
Calmodulin Binding
Adenylate Cyclase Binding
Protein Kinase A Binding
Biological Process
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Regulation Of Protein Kinase A Signaling
Positive Regulation Of Protein Kinase A Signaling
Response To Lipopolysaccharide
Hepatic Stellate Cell Activation
Negative Regulation Of Vascular Permeability
Modulation Of Chemical Synaptic Transmission
Response To Electrical Stimulus
Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process
Positive Regulation Of Hepatic Stellate Cell Migration
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Regulation Of Protein Kinase C Signaling
Positive Regulation Of Oligodendrocyte Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Alzheimer's disease progression score (
29860282
)
Blond vs. brown/black hair color (
30531825
)
Brown vs. black hair color (
30531825
)
Chronic myeloid leukemia (
21540461
)
Coronary artery disease (
29212778
)
Cutaneous malignant melanoma (
32341527
)
Cutaneous melanoma or hair colour (
32341527
)
Delirium (
29631748
)
Heel bone mineral density (
30598549
)
Nevus count or cutaneous melanoma (
32341527
)
Refractive error (
32231278
)
Type 2 diabetes (
25760438
)
Youthful appearance (self-reported) (
32339537
)
Novel Interacting Genes
1 novel interacting genes:
SYNE1
Interacting Genes
8 interacting genes:
ADRB2
EGFR
ERBB2
FHL1
GRK2
PRKAR2A
PRKCA
PTEN
Entrez ID
9590
HPRD ID
05263
Ensembl ID
ENSG00000131016
Uniprot IDs
Q02952
Q86TJ9
PDB IDs
Enriched GO Terms of Interacting Partners
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