PKD2L1

Description		polycystin 2 like 1, transient receptor potential cation channel
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Cytoplasmic Vesicle Calcium Channel Complex Intracellular Membrane-bounded Organelle Receptor Complex Ciliary Membrane Non-motile Cilium
	Molecular Function	Calcium Activated Cation Channel Activity Cation Channel Activity Calcium Channel Activity Sodium Channel Activity Calcium Ion Binding Protein Binding Cytoskeletal Protein Binding Cation Transmembrane Transporter Activity Calcium-activated Potassium Channel Activity Sour Taste Receptor Activity Identical Protein Binding Muscle Alpha-actinin Binding Alpha-actinin Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Sour Taste Cation Transport Smoothened Signaling Pathway Response To Water Sodium Ion Transmembrane Transport Detection Of Chemical Stimulus Involved In Sensory Perception Of Taste Sensory Perception Of Sour Taste Detection Of Mechanical Stimulus Protein Homotetramerization Calcium Ion Transmembrane Transport Cellular Response To Acidic PH Potassium Ion Transmembrane Transport Inorganic Cation Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778 33020668) Diastolic blood pressure ( 30224653) Fatty acid desaturase activity (adipose tissue) ( 30453627) Glycerophospholipid levels ( 26068415) Heel bone mineral density ( 30598549 28869591) Low density lipoprotein cholesterol levels ( 32154731) Lymphocyte counts ( 32888494) Macular thickness ( 30535121) Mean platelet volume ( 32888494 27863252) Monocyte count ( 32888494) Obesity-related traits ( 23251661) Palmitic acid (16:0) levels ( 23362303) Palmitoleic acid (16:1n-7) levels ( 28298293 23362303) Phospholipid levels (plasma) ( 22359512) Red cell distribution width ( 32888494) Refractive error ( 32231278) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Serum metabolite levels ( 24625756) Serum metabolite levels (CMS) ( 31636271) Serum metabolite ratios in chronic kidney disease ( 29545352) Squamous cell lung carcinoma ( 28604730) Vaccenic acid (18:1n-7) levels ( 28298293)
Interacting Genes		4 interacting genes: CLDN19 TNNI1 TNNI2 TNNI3
Entrez ID		9033
HPRD ID		16063
Ensembl ID		ENSG00000107593
Uniprot IDs		Q1L4F0 Q9P0L9
PDB IDs		3TE3 4GIF 6DU8
Enriched GO Terms of Interacting Partners?
Tagcloud ?