IL18RAP

Description		interleukin 18 receptor accessory protein
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GO Annotations	Cellular Component	Plasma Membrane Interleukin-18 Receptor Complex
	Molecular Function	Protein Binding Interleukin-18 Receptor Activity NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating
	Biological Process	Inflammatory Response Immune Response Cell Population Proliferation Interleukin-18-mediated Signaling Pathway Neutrophil Activation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of NF-kappaB Transcription Factor Activity Cellular Response To Hydrogen Peroxide
Pathways		Interleukin-18 signaling
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Allergic sensitization ( 23817571) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23042114 26482879) Basophil percentage of white cells ( 32888494) Blood protein levels ( 30072576 28240269) Celiac disease ( 22057235 20190752 18311140) Crohn's disease ( 28067908 21102463) Delirium ( 29631748) Extranodal natural killer T-cell lymphoma (nasal type) ( 31879220) Inflammatory bowel disease ( 28067908 23128233) Leprosy ( 25642632) Liver fibrosis in pediatric non-alcoholic fatty acid liver disease ( 28918882) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 27863252) Monocyte count ( 32888494) Primary biliary cholangitis ( 26394269) Serum protein levels (sST2) ( 23999434) Systemic lupus erythematosus ( 28714469)
Novel Interacting Genes		1 novel interacting genes: AFF3
Interacting Genes		4 interacting genes: APP CD48 IL18 TRIM54
Entrez ID		8807
HPRD ID		05147
Ensembl ID		ENSG00000115607
Uniprot IDs		O95256
PDB IDs		3WO4 6KN9
Enriched GO Terms of Interacting Partners?
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