TNFRSF6B

Description		TNF receptor superfamily member 6b
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Signaling Receptor Activity
	Biological Process	Apoptotic Process Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Apoptotic Process
Pathways		TNFs bind their physiological receptors
Drugs
Diseases		Autoimmune lymphoproliferative syndromes (ALPS), including the following five diseases: CD95 (Fas) defect, ALPS type 1a; CD95L (Fas ligand) defect, ALPS type 1b; Caspase 10 defect, ALPS type 2a; Caspase 8 defext, ALPS type 2b; Activaing N-Ras defect, N-Ras ALPS
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31361310 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 25574825 26482879 23727859) Blood protein levels ( 30072576 29875488) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Glioma ( 22886559) Inflammatory bowel disease ( 18758464 28067908 23128233) Pediatric autoimmune diseases ( 26301688) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908 21297633)
Interacting Genes		6 interacting genes: FASLG KRTAP10-3 KRTAP10-9 PPP1R7 TNFSF14 TNFSF15
Entrez ID		8771
HPRD ID		04527
Ensembl ID		ENSG00000243509
Uniprot IDs		O95407
PDB IDs		3K51 3MHD 3MI8 4J6G 4KGG 4KGQ 4MSV 5L36
Enriched GO Terms of Interacting Partners?
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