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NKD1

Description NKD inhibitor of WNT signaling pathway 1
Image No pdb structure
GO Annotations Cellular Component
  • Protein Phosphatase Type 2A Complex
  • Cytoplasm
  • Plasma Membrane
Molecular Function
  • Calcium Ion Binding
  • Protein Binding
  • PDZ Domain Binding
Biological Process
  • Eye Photoreceptor Cell Differentiation
  • Somatic Muscle Development
  • Wnt Signaling Pathway
  • Negative Regulation Of Wnt Signaling Pathway
  • Positive Regulation Of Protein Catabolic Process
  • Negative Regulation Of Canonical Wnt Signaling Pathway
  • Regulation Of Cell Migration Involved In Somitogenic Axis Elongation
  • Positive Regulation Of Non-canonical Wnt Signaling Pathway Via JNK Cascade
  • Negative Regulation Of Convergent Extension Involved In Axis Elongation
  • Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways
Drugs
Diseases
GWAS
  • Copper levels ( 26025379)
  • Crohn's disease ( 28067908 22412388)
  • Inflammatory bowel disease ( 28067908)
  • Systolic blood pressure ( 30224653)
Interacting Genes 14 interacting genes: CYSRT1 DVL3 KRTAP10-1 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 KRTAP9-8 MDFI MORF4L1
Entrez ID 85407
HPRD ID 08482
Ensembl ID ENSG00000140807
Uniprot IDs Q969G9
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025