DOCK5

Description		dedicator of cytokinesis 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of Epithelial Cell Migration Cell Migration Positive Regulation Of GTPase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Vascular Associated Smooth Muscle Contraction Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778 33020668) Glucose homeostasis traits ( 25524916) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Length of menstrual cycle ( 30202859) Lymphocyte percentage of white cells ( 32888494) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) QT interval ( 29213071) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		1 interacting genes: ATXN1
Entrez ID		80005
HPRD ID		09925
Ensembl ID		ENSG00000147459
Uniprot IDs		B9A015 Q68DL4 Q9H7D0
PDB IDs
Enriched GO Terms of Interacting Partners?
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