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LPCAT1
Description
lysophosphatidylcholine acyltransferase 1
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Lipid Droplet
Plasma Membrane
Membrane
Integral Component Of Membrane
Azurophil Granule Membrane
Molecular Function
1-acylglycerol-3-phosphate O-acyltransferase Activity
Calcium Ion Binding
1-alkenylglycerophosphocholine O-acyltransferase Activity
1-acylglycerophosphocholine O-acyltransferase Activity
1-alkylglycerophosphocholine O-acyltransferase Activity
1-alkylglycerophosphocholine O-acetyltransferase Activity
Plasmalogen Synthase Activity
Biological Process
Phosphatidic Acid Biosynthetic Process
Phosphatidylcholine Biosynthetic Process
Phospholipid Biosynthetic Process
Phosphatidylglycerol Acyl-chain Remodeling
Phosphatidylcholine Acyl-chain Remodeling
Surfactant Homeostasis
Neutrophil Degranulation
Positive Regulation Of Protein Catabolic Process
Retina Development In Camera-type Eye
Negative Regulation Of Phosphatidylcholine Biosynthetic Process
Pathways
Acyl chain remodelling of PC
Acyl chain remodelling of PG
Synthesis of PA
Synthesis of PC
Neutrophil degranulation
Drugs
Diseases
GWAS
Lung adenocarcinoma (
28604730
)
Lung cancer in ever smokers (
28604730
)
Multiple sclerosis (
31604244
)
Pancreatic cancer (
25086665
)
Interacting Genes
2 interacting genes:
BTRC
GSK3B
Entrez ID
79888
HPRD ID
08572
Ensembl ID
ENSG00000153395
Uniprot IDs
D3DTC2
Q8NF37
PDB IDs
Enriched GO Terms of Interacting Partners
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