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FA2H

Description fatty acid 2-hydroxylase
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Membrane
  • Integral Component Of Membrane
Molecular Function
  • Iron Ion Binding
  • Protein Binding
  • Heme Binding
  • Fatty Acid Alpha-hydroxylase Activity
Biological Process
  • Sebaceous Gland Cell Differentiation
  • Fatty Acid Metabolic Process
  • Fatty Acid Biosynthetic Process
  • Glucosylceramide Biosynthetic Process
  • Galactosylceramide Biosynthetic Process
  • Sphingolipid Biosynthetic Process
  • Lipid Modification
  • Central Nervous System Myelin Maintenance
  • Peripheral Nervous System Myelin Maintenance
  • Regulation Of Cell Population Proliferation
  • Regulation Of Hair Cycle
  • Plasma Membrane Raft Organization
  • Ceramide Biosynthetic Process
  • Establishment Of Skin Barrier
Pathways
  • Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
  • General cognitive ability ( 25383866)
  • Pancreatic cancer ( 25086665)
  • White matter lesion progression (adjusted for white matter lesion burden at baseline) ( 26451028)
Interacting Genes 31 interacting genes: AQP6 ARMC12 ASGR2 CD79A CREB3 CREB3L1 DLG2 EBP ELOVL4 ERGIC3 ERLIN1 FAM209A FCER1G GPR152 GPR37 GPX8 LMNA MARCHF8 MSR1 PEX12 PGRMC2 RIC3 SGPL1 SLC10A1 SLC10A6 SYT2 TLCD4 TMEM14B TMEM41A TMX2 UBQLN4
Entrez ID 79152
HPRD ID 16873
Ensembl ID ENSG00000103089
Uniprot IDs Q7L5A8
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025