ALG8

Description		ALG8 alpha-1,3-glucosyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Alpha-1,3-mannosyltransferase Activity Dolichyl-phosphate-glucose-glycolipid Alpha-glucosyltransferase Activity Protein Binding Dolichyl Pyrophosphate Glc1Man9GlcNAc2 Alpha-1,3-glucosyltransferase Activity
	Biological Process	Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Oligosaccharide-lipid Intermediate Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Mannosylation
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG8 causes ALG8-CDG (CDG-1h)
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type I
GWAS		Depression in smokers ( 30219690) Tourette syndrome ( 30818990)
Novel Interacting Genes		4 novel interacting genes: IQGAP2 NARS2 RSF1 TMEM126B
Interacting Genes		12 interacting genes: BIK CLRN1 CREB3 CREB3L1 CYB5R3 FAM209A GPX8 LMNA MFSD6 NAE1 RPS6KA5 SAR1A
Entrez ID		79053
HPRD ID		10480
Ensembl ID		ENSG00000159063
Uniprot IDs		A0A024R5K5 Q9BVK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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