TRPS1

Description		transcriptional repressor GATA binding 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Regulation Of Transcription By RNA Polymerase II Regulation Of Chondrocyte Differentiation
Pathways
Drugs
Diseases		Trichorhinophalangeal dysplasia
GWAS		Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Asthma ( 29273806) Basal cell carcinoma ( 31174203) Brain morphology (MOSTest) ( 32665545) Bronchopulmonary dysplasia ( 23897914) C-reactive protein levels ( 30388399) Cholesterol, total ( 20686565) Chronotype ( 30696823) Cognitive decline (age-related) ( 28078323) Cutaneous squamous cell carcinoma ( 27424798 32041948) Disability (impaired activities of daily living) ( 31707593) Diverticular disease ( 30177863) Eating disorders ( 22911880) Granulocyte percentage of myeloid white cells ( 27863252) Hand grip strength ( 29691431) HDL cholesterol ( 24097068 30275531 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High density lipoprotein cholesterol levels ( 29403010) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Keratinocyte cancer (MTAG) ( 31174203) LDL cholesterol levels ( 32203549) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Low density lipoprotein cholesterol levels ( 32154731) Low tan response ( 29739929) Major depressive disorder ( 22472876) Male-pattern baldness ( 28196072) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolic syndrome ( 31589552) Metabolite levels ( 23823483) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Morning person ( 30696823) Night sleep phenotypes ( 27126917) Parkinson's disease (familial, age at onset) ( 27402877) Periodontal microbiota ( 22699663) Platelet count ( 29403010) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511) Red blood cell count ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Severe influenza A (H1N1) infection ( 26379185) Squamous cell carcinoma ( 31174203) Total cholesterol levels ( 29403010 30275531) Triglyceride levels ( 32203549) Urate levels (BMI interaction) ( 25811787) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		3 interacting genes: RNF4 SUMO1 UBE2I
Entrez ID		7227
HPRD ID		05091
Ensembl ID		ENSG00000104447
Uniprot IDs		Q9UHF7
PDB IDs
Enriched GO Terms of Interacting Partners?
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