SNAI2

Description		snail family transcriptional repressor 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Metal Ion Binding E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Epithelial To Mesenchymal Transition Aortic Valve Morphogenesis Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Cell Migration Involved In Endocardial Cushion Formation Regulation Of Transcription, DNA-templated Notch Signaling Pathway Sensory Perception Of Sound Negative Regulation Of Keratinocyte Proliferation Negative Regulation Of Vitamin D Biosynthetic Process Neural Crest Cell Development Positive Regulation Of Cell Migration Negative Regulation Of Chondrocyte Differentiation Regulation Of Chemokine Production Negative Regulation Of Cell Adhesion Mediated By Integrin Desmosome Disassembly Pigmentation Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Osteoblast Differentiation Epithelium Development Notch Signaling Involved In Heart Development Negative Regulation Of Vitamin D Receptor Signaling Pathway Cellular Response To Epidermal Growth Factor Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Bicellular Tight Junction Assembly Negative Regulation Of Anoikis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases		Piebaldism Waardenburg syndrome (WS)
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252)
Novel Interacting Genes		1 novel interacting genes: SMG6
Interacting Genes		11 interacting genes: APP CABP2 CSNK2A1 PIAS1 PIAS2 PIAS3 PIAS4 SAT1 TRIM23 UBE2I ZNF76
Entrez ID		6591
HPRD ID		03689
Ensembl ID		ENSG00000019549
Uniprot IDs		O43623
PDB IDs
Enriched GO Terms of Interacting Partners?
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