SLC11A1

Description		solute carrier family 11 member 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Late Endosome Plasma Membrane Integral Component Of Plasma Membrane Phagocytic Vesicle Membrane Late Endosome Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Iron Ion Transmembrane Transporter Activity Manganese Ion Transmembrane Transporter Activity Cadmium Ion Transmembrane Transporter Activity Protein Homodimerization Activity Transition Metal Ion Transmembrane Transporter Activity Metal Ion:proton Antiporter Activity
	Biological Process	Negative Regulation Of Cytokine Production Positive Regulation Of Cytokine Production T Cell Proliferation Involved In Immune Response Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Positive Regulation Of T-helper 1 Type Immune Response Iron Ion Transport Manganese Ion Transport Cellular Cadmium Ion Homeostasis Cellular Iron Ion Homeostasis Phagocytosis Inflammatory Response Vacuolar Acidification Response To Bacterium Positive Regulation Of Gene Expression Nitrite Transport Antimicrobial Humoral Response Activation Of Protein Kinase Activity Response To Lipopolysaccharide Positive Regulation Of Interferon-gamma Production Response To Interferon-gamma Iron Ion Transmembrane Transport Wound Healing Macrophage Activation Defense Response To Bacterium Defense Response To Protozoan Neutrophil Degranulation MHC Class II Biosynthetic Process Cell Redox Homeostasis Respiratory Burst Positive Regulation Of Transcription By RNA Polymerase II Antigen Processing And Presentation Of Peptide Antigen MRNA Stabilization Positive Regulation Of Phagocytosis Defense Response To Gram-negative Bacterium Iron Ion Homeostasis Multicellular Organismal Iron Ion Homeostasis Cadmium Ion Transmembrane Transport Metal Ion Export Manganese Ion Transmembrane Transport L-arginine Transport
Pathways		ROS and RNS production in phagocytes Metal ion SLC transporters Neutrophil degranulation Ion influx/efflux at host-pathogen interface
Drugs
Diseases		Tuberculosis
GWAS		Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 21297633)
Novel Interacting Genes		1 novel interacting genes: TUBA4A
Interacting Genes
Entrez ID		6556
HPRD ID		02601
Ensembl ID		ENSG00000018280
Uniprot IDs		P49279
PDB IDs
Enriched GO Terms of Interacting Partners?
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