SLC2A2

Description		solute carrier family 2 member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Brush Border Cell-cell Junction Membrane Apical Plasma Membrane
	Molecular Function	Fructose Transmembrane Transporter Activity Glucose Transmembrane Transporter Activity Dehydroascorbic Acid Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity
	Biological Process	Carbohydrate Metabolic Process Hexose Transmembrane Transport Fructose Transmembrane Transport Regulation Of Insulin Secretion Dehydroascorbic Acid Transport Intestinal Hexose Absorption Glucose Transmembrane Transport
Pathways		Cellular hexose transport Regulation of gene expression in beta cells Regulation of insulin secretion Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS) Intestinal hexose absorption
Drugs		Streptozocin
Diseases		Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Adult body size ( 32376654) Blood sugar levels ( 29403010) C-reactive protein levels ( 30388399) Fasting blood glucose ( 25631608 20081858 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Fasting plasma glucose ( 28270201) Glycated hemoglobin levels ( 28898252) Hemoglobin A1c levels ( 29403010) Homeostasis model assessment of beta-cell function ( 20081858) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Night sleep phenotypes ( 27126917) Response to metformin in type 2 diabetes (HbA1c reduction) ( 27500523) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Type 2 diabetes ( 30297969 32499647)
Novel Interacting Genes		1 novel interacting genes: SUZ12
Interacting Genes		4 interacting genes: APP KPNA2 PDX1 PRKACA
Entrez ID		6514
HPRD ID		00685
Ensembl ID		ENSG00000163581
Uniprot IDs		P11168 Q6PAU8
PDB IDs
Enriched GO Terms of Interacting Partners?
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