P2RY12

Description		purinergic receptor P2Y12
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GO Annotations	Cellular Component	Mitochondrion Plasma Membrane Caveola External Side Of Plasma Membrane Basal Plasma Membrane Cell Surface Integral Component Of Membrane Intrinsic Component Of Membrane Cell Projection Membrane Cell Body Membrane
	Molecular Function	G Protein-coupled Adenosine Receptor Activity G Protein-coupled ADP Receptor Activity Guanyl-nucleotide Exchange Factor Activity G Protein-coupled Purinergic Nucleotide Receptor Activity
	Biological Process	G Protein-coupled Adenosine Receptor Signaling Pathway Substrate-dependent Cell Migration, Cell Extension G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Hemostasis Negative Regulation Of Norepinephrine Secretion Calcium-mediated Signaling Cytosolic Calcium Signaling Involved In Initiation Of Cell Movement In Glial-mediated Radial Cell Migration Cell Projection Organization Lamellipodium Assembly Positive Regulation Of Integrin Activation By Cell Surface Receptor Linked Signal Transduction Positive Regulation Of Cell Adhesion Mediated By Integrin Calcium-mediated Signaling Using Extracellular Calcium Source G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway Positive Regulation Of Ion Transport Protein Kinase B Signaling Positive Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of Cell Differentiation Response To Axon Injury Regulation Of Chemotaxis Positive Regulation Of Chemotaxis Positive Regulation Of Protein Kinase B Signaling Regulation Of Calcium Ion Transport Platelet Aggregation Calcium Ion Transmembrane Transport Cellular Response To ATP Potassium Ion Transmembrane Transport Visual System Development Positive Regulation Of Ruffle Assembly Microglial Cell Migration Regulation Of Microglial Cell Migration Positive Regulation Of Microglial Cell Migration
Pathways		ADP signalling through P2Y purinoceptor 12 P2Y receptors G alpha (i) signalling events
Drugs		Ticlopidine Treprostinil Clopidogrel Promethazine Epoprostenol Regrelor Prasugrel Elinogrel Cangrelor Ticagrelor
Diseases
GWAS		Diverticular disease ( 30177863)
Interacting Genes		1 interacting genes: GNAI2
Entrez ID		64805
HPRD ID		02743
Ensembl ID		ENSG00000169313
Uniprot IDs		A8K7T1 Q9H244
PDB IDs		1T78 1VZ1 1Y9C 4NTJ 4PXZ 4PY0
Enriched GO Terms of Interacting Partners?
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