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SFTPC

Description surfactant protein C
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Endoplasmic Reticulum Membrane
  • Lamellar Body
  • Clathrin-coated Endocytic Vesicle
  • Alveolar Lamellar Body
  • Multivesicular Body Lumen
Molecular Function
  • Protein Binding
  • Identical Protein Binding
Biological Process
  • Respiratory Gaseous Exchange By Respiratory System
  • Cellular Protein Metabolic Process
Pathways
  • Surfactant metabolism
  • Defective pro-SFTPC causes SMDP2 and RDS
  • Defective CSF2RB causes SMDP5
  • Defective CSF2RA causes SMDP4
Drugs
Diseases
  • Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS
  • Coronary artery disease ( 29212778)
  • Hypertriglyceridemia ( 23505323)
Interacting Genes 36 interacting genes: BSCL2 CD200R1 CD79A CLDN5 CPLX4 CREB3 CXCL9 FAM209A FNDC9 GJA8 GOLM1 GPR152 GPX8 HPN ICAM3 IFNGR2 KLRC1 LMNA LSMEM2 MUC1 NEDD4 PDZK1IP1 PQBP1 PVR SEC22A SEC61G SIGLEC9 SMIM3 SYNE4 TMEM106C TMEM139 TMEM30B TMEM79 TMPRSS2 WWP1 WWP2
Entrez ID 6440
HPRD ID 01520
Ensembl ID ENSG00000168484
Uniprot IDs A0A0A0MTC9 A0A0S2Z4Q0 E5RI64 P11686
PDB IDs 2YAD
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025