HSD17B12

Description		hydroxysteroid 17-beta dehydrogenase 12
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Fatty Acid Elongase Complex Integral Component Of Membrane Extracellular Matrix
	Molecular Function	Fibronectin Binding Estradiol 17-beta-dehydrogenase Activity Protein Binding Collagen Binding Heparin Binding Long-chain-fatty-acyl-CoA Reductase Activity 3-oxo-arachidoyl-CoA Reductase Activity 3-oxo-behenoyl-CoA Reductase Activity 3-oxo-lignoceroyl-CoA Reductase Activity 3-oxo-cerotoyl-CoA Reductase Activity
	Biological Process	Fatty Acid Biosynthetic Process Estrogen Biosynthetic Process Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Long-chain Fatty-acyl-CoA Biosynthetic Process
Pathways		Androgen biosynthesis Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Adult body size ( 32376654) Birth length ( 25281659) Body mass index ( 26961502 25673413 29273807) Chronotype ( 30696823) Coronary artery disease ( 29212778 33020668) Essential hypertension (time to event) ( 32589924) FEV1 ( 30804560) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Lung function (forced vital capacity) ( 24929828) Lung function (FVC) ( 30804560) Morning person ( 30696823) Neuroblastoma ( 22941191) Neuroblastoma or malignant cutaneous melanoma ( 31605138) Sporadic neuroblastoma ( 28545128) Type 2 diabetes ( 28566273 30297969) Waist circumference ( 28552196)
Novel Interacting Genes		1 novel interacting genes: AMBRA1
Interacting Genes		2 interacting genes: UBQLN1 UBQLN2
Entrez ID		51144
HPRD ID		09989
Ensembl ID		ENSG00000149084
Uniprot IDs		Q53GQ0
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?