ACOX1

Description		acyl-CoA oxidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane
	Molecular Function	Acyl-CoA Oxidase Activity Fatty Acid Binding Palmitoyl-CoA Oxidase Activity PDZ Domain Binding Protein Homodimerization Activity Protein N-terminus Binding Flavin Adenine Dinucleotide Binding FAD Binding
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Generation Of Precursor Metabolites And Energy Protein Targeting To Peroxisome Lipid Metabolic Process Prostaglandin Metabolic Process Spermatogenesis Fatty Acid Catabolic Process Regulation Of Lipid Metabolic Process Fatty Acid Oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process Hydrogen Peroxide Biosynthetic Process Lipid Homeostasis
Pathways		Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins
Drugs		Flavin adenine dinucleotide (3R)-3-HYDROXYDODECANOIC ACID
Diseases		Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
GWAS		Body mass index ( 28552196) Diastolic blood pressure ( 27841878) Mean platelet volume ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 28135244 27841878) Urinary metabolite levels in chronic kidney disease ( 31959995) White matter hyperintensity burden ( 25663218)
Interacting Genes		3 interacting genes: SCP2 SLC2A4 TYSND1
Entrez ID		51
HPRD ID		02030
Ensembl ID		ENSG00000161533
Uniprot IDs		Q15067
PDB IDs
Enriched GO Terms of Interacting Partners?
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