NDUFS4

Description		NADH:ubiquinone oxidoreductase subunit S4
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Regulation Of Protein Phosphorylation Mitochondrial Electron Transport, NADH To Ubiquinone Brain Development CAMP-mediated Signaling Mitochondrial Respiratory Chain Complex I Assembly Cellular Respiration Positive Regulation Of Fibroblast Proliferation Response To CAMP Reactive Oxygen Species Metabolic Process
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Acne (severe) ( 24927181) Blond vs. brown/black hair color ( 30531825) Midgestational circulating levels of PCBs ( 28235828) Monobrow ( 27182965) Night sleep phenotypes ( 27126917) Verbal memory ( 29907492) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500)
Interacting Genes		2 interacting genes: APP UBE2G2
Entrez ID		4724
HPRD ID		04073
Ensembl ID		ENSG00000164258
Uniprot IDs		A0A0S2Z433 O43181
PDB IDs		5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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