MYH11

Description		myosin heavy chain 11
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Muscle Myosin Complex Myosin Filament Melanosome Extracellular Exosome
	Molecular Function	Motor Activity Protein Binding Calmodulin Binding ATP Binding Structural Constituent Of Muscle Actin Filament Binding
	Biological Process	Muscle Contraction Smooth Muscle Contraction Skeletal Muscle Myosin Thick Filament Assembly Elastic Fiber Assembly Cardiac Muscle Fiber Development
Pathways		EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse Smooth Muscle Contraction RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs		Tetrafluoroaluminate Ion
Diseases		Familial thoracic aortic aneurysm and dissection (TAAD); Aortic aneurysm familial thoracic type (AAT)
GWAS		Cognitive function ( 25644384) Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Multiple myeloma (survival) ( 26198393) Pelvic organ prolapse (moderate/severe) ( 26545240) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) PR interval ( 32439900) Pulse pressure ( 27841878 30578418) Resting heart rate ( 29769521 27798624) Serum immune biomarker levels ( 32066700) Serum uric acid levels in response to allopurinol in gout ( 25676789) Skin aging measurement ( 31522824) Waist-hip ratio ( 23966867)
Interacting Genes		4 interacting genes: APC DAXX GRB2 MAPKAPK5
Entrez ID		4629
HPRD ID		01174
Ensembl ID		ENSG00000133392
Uniprot IDs		A0A024QZJ4 A0A024QZJ6 P35749
PDB IDs
Enriched GO Terms of Interacting Partners?
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