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MT-CO1

Description cytochrome c oxidase subunit I
Image
GO Annotations Cellular Component
  • Mitochondrial Inner Membrane
  • Mitochondrial Respiratory Chain Complex III
  • Mitochondrial Respiratory Chain Complex IV
  • Integral Component Of Membrane
  • Respiratory Chain Complex IV
Molecular Function
  • Cytochrome-c Oxidase Activity
  • Protein Binding
  • Heme Binding
  • Metal Ion Binding
Biological Process
  • Mitochondrial Electron Transport, Cytochrome C To Oxygen
  • Response To Oxidative Stress
  • Aging
  • Aerobic Respiration
  • Electron Transport Coupled Proton Transport
  • Cerebellum Development
  • Respiratory Electron Transport Chain
  • Response To Copper Ion
  • Response To Electrical Stimulus
Pathways
  • TP53 Regulates Metabolic Genes
  • Respiratory electron transport
Drugs
  • Cholic Acid
  • N-Formylmethionine
  • Oxygen
Diseases
  • Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS
Novel Interacting Genes 1 novel interacting genes: MAPK8
Interacting Genes 10 interacting genes: CDC42 CLEC4G COX4I1 COX5A HSPB2 KCNMB1 LIG4 MEOX2 PRDX4 SNCA
Entrez ID 4512
HPRD ID 02469
Ensembl ID ENSG00000198804
Uniprot IDs A0A1X7RBG2 P00395 U5YWV7
PDB IDs 5Z62
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025