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MAX
Description
MYC associated factor X
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
PML Body
Dendrite
Protein-DNA Complex
MLL1 Complex
RNA Polymerase II Transcription Regulator Complex
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Identical Protein Binding
Protein-containing Complex Binding
Protein Dimerization Activity
E-box Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Cellular Response To Starvation
Response To Insulin
Positive Regulation Of Transcription By RNA Polymerase II
Response To Axon Injury
Neuron Apoptotic Process
Retina Development In Camera-type Eye
Protein-containing Complex Assembly
Negative Regulation Of G0 To G1 Transition
Cellular Response To Peptide Hormone Stimulus
Pathways
Transcription of E2F targets under negative control by DREAM complex
Cyclin E associated events during G1/S transition
Cyclin A:Cdk2-associated events at S phase entry
Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS
Anthropometric traits (
19260139
)
Blood protein levels (
30072576
)
Blood trace element (Zn levels) (
23720494
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Height (
31562340
)
Hemoglobin (
32888494
)
Hemoglobin levels (
32327693
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Immature fraction of reticulocytes (
32888494
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular hemoglobin concentration (
29403010
32888494
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Mean platelet volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Neutrophil count (
32888494
)
Obesity-related traits (
23251661
)
Platelet count (
32888494
27863252
)
Red blood cell count (
32888494
27863252
)
Red blood cell traits (
23222517
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
White blood cell count (
32888494
)
Interacting Genes
42 interacting genes:
BANP
CASP5
CASP7
CLIP2
COPS5
CSNK2A1
CUX1
EP300
EPAS1
FTH1
FUS
GABBR1
HIF1A
MAD1L1
MAPK14
MGA
MNT
MSH2
MXD1
MXD3
MXD4
MXI1
MYC
MYCL
MYCLP1
MYCN
PLEKHA5
PLEKHF2
PLIN3
RPL34
RPL35
SMAD3
SMAD4
SNIP1
SPAG9
TAF1
TEAD1
TRRAP
TUBA1A
TXLNG
UNC45A
ZBTB17
Entrez ID
4149
HPRD ID
01113
Ensembl ID
ENSG00000125952
Uniprot IDs
A0A024R682
G3V302
P61244
Q8TAX8
PDB IDs
1AN2
1HLO
1NKP
1NLW
1R05
5EYO
6G6J
6G6K
6G6L
Enriched GO Terms of Interacting Partners
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