LMX1B

Description		LIM homeobox transcription factor 1 beta
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	In Utero Embryonic Development Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Dorsal/ventral Pattern Formation Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Dopaminergic Neuron Differentiation
Pathways
Drugs
Diseases		Patella dysplasias, including: Small patella syndrome (SPS); Nail-patella syndrome; Ear-patella-short statute syndrome
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Adult body size ( 32376654) Body fat mass ( 28552196) Body mass index ( 28552196 26961502 28892062 25673413 20935630) Body size at age 10 ( 32376654) Breast cancer ( 29059683 31757997) Calcium levels ( 29403010) Childhood body mass index ( 33045005 26604143) Chin dimples ( 27182965) Eyebrow thickness ( 26926045) Glaucoma ( 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 29891935 29449654) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 29785010 31959993 30054594) Medication use (antiglaucoma preparations and miotics) ( 31015401) Monobrow ( 27182965) Multiple system atrophy ( 27629089) Open-angle glaucoma and optic cup area ( 29449654) Osteoarthritis (hip) ( 30374069) Social communication problems ( 24564958) Trunk fat mass ( 28552196)
Interacting Genes		5 interacting genes: APP CREB5 HOXA1 LDB1 TCF3
Entrez ID		4010
HPRD ID		03986
Ensembl ID		ENSG00000136944
Uniprot IDs		B7ZLH2 O60663 Q6ISE0
PDB IDs
Enriched GO Terms of Interacting Partners?
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