PDE7B

Description		phosphodiesterase 7B
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GO Annotations	Cellular Component	Cytosol Synapse
	Molecular Function	3',5'-cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-AMP Phosphodiesterase Activity Metal Ion Binding
	Biological Process	CAMP Catabolic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Chemical Synaptic Transmission CAMP-mediated Signaling
Pathways		G alpha (s) signalling events
Drugs		Caffeine Trapidil
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Aspartate aminotransferase levels ( 31219225) Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) BRCA1/2-negative high-risk breast cancer ( 30323354) Delirium ( 29631748) Diverticulitis ( 28585551) Glaucoma ( 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 29891935) Heel bone mineral density ( 30598549 28869591) Hemoglobin levels ( 32327693) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Intraocular pressure ( 29617998 24002674 29785010 31959993 30054594) Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Phosphorus levels ( 20558539)
Interacting Genes		1 interacting genes: SRPK2
Entrez ID		27115
HPRD ID		06870
Ensembl ID		ENSG00000171408
Uniprot IDs		Q9NP56
PDB IDs		1LXW
Enriched GO Terms of Interacting Partners?
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