DNM3

Description		dynamin 3
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GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Microtubule Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Mitochondrial Membrane Synaptic Cleft Dendritic Spine Dendritic Spine Head Perinuclear Region Of Cytoplasm Apical Tubulobulbar Complex Basal Tubulobulbar Complex Extracellular Exosome Presynapse Postsynaptic Endocytic Zone Membrane Glutamatergic Synapse
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding Type 1 Metabotropic Glutamate Receptor Binding Type 5 Metabotropic Glutamate Receptor Binding Nitric-oxide Synthase Binding Structural Constituent Of Postsynapse
	Biological Process	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Endocytosis Synapse Assembly Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Filopodium Assembly Regulation Of Synapse Structure Or Activity Positive Regulation Of Filopodium Assembly Negative Regulation Of Dendritic Spine Morphogenesis Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization Postsynapse Organization Positive Regulation Of Synaptic Vesicle Recycling
Pathways		Toll Like Receptor 4 (TLR4) Cascade Retrograde neurotrophin signalling MHC class II antigen presentation Recycling pathway of L1 Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Diastolic blood pressure ( 28135244 27841878) Estimated glomerular filtration rate ( 31152163) Femoral neck bone mineral density ( 22504420) Heel bone mineral density ( 30598549 28869591) Height ( 28552196 20881960 25282103 25429064 23563607 31562340 18391951) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High density lipoprotein cholesterol levels ( 29083408) Hip circumference adjusted for BMI ( 25673412) Mean platelet volume ( 22139419 24026423 19820697 32888494 27863252) Ovarian cancer ( 30557369) Platelet count ( 22139419 29403010 32888494 27863252) Platelet distribution width ( 32888494 27863252) QT interval (sulfonylurea treatment interaction) ( 27958378) Red blood cell count ( 32888494) Systolic blood pressure ( 27841878) Triglyceride levels ( 32203549) Uterine fibroids ( 31249589) Very long-chain saturated fatty acid levels (fatty acid 22:0) ( 25378659) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500) Waist-hip ratio ( 25673412 20935629) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes		2 interacting genes: DYNLL1 HOMER1
Entrez ID		26052
HPRD ID		13241
Ensembl ID		ENSG00000197959
Uniprot IDs		Q9UQ16
PDB IDs		3L43 5A3F
Enriched GO Terms of Interacting Partners?
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