SPDEF

Description		SAM pointed domain containing ETS transcription factor
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GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Negative Regulation Of Cell Fate Commitment Positive Regulation Of Cell Fate Commitment Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Lung Goblet Cell Differentiation Intestinal Epithelial Cell Development
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Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 28552196) Inflammatory bowel disease ( 27569725) Refractive error ( 32231278) Weight ( 28552196)
Novel Interacting Genes		1 novel interacting genes: ESR1
Interacting Genes		12 interacting genes: AR CEP57 COX5A ENKD1 FAM161B NKX3-1 PCGF2 PSMA1 SNX20 SRPK2 STK11 TTC23
Entrez ID		25803
HPRD ID		12176
Ensembl ID		ENSG00000124664
Uniprot IDs		O95238
PDB IDs		1YO5 2DKX
Enriched GO Terms of Interacting Partners?
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