QPCT

Description		glutaminyl-peptide cyclotransferase
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GO Annotations	Cellular Component	Extracellular Region Specific Granule Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Zinc Ion Binding Glutaminyl-peptide Cyclotransferase Activity
	Biological Process	Cellular Protein Modification Process Peptidyl-pyroglutamic Acid Biosynthetic Process, Using Glutaminyl-peptide Cyclotransferase Protein Phosphopantetheinylation Neutrophil Degranulation
Pathways		Neutrophil degranulation
Drugs		1-benzylimidazole N-acetylhistamine Glutamine t-butyl ester
Diseases
GWAS		Blood protein levels ( 30072576) Body mass index ( 28892062) Chronic lymphocytic leukemia ( 28165464 26956414 24292274) Height ( 31562340) Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225) Schizophrenia ( 30285260 23974872)
Novel Interacting Genes		1 novel interacting genes: CFLAR
Interacting Genes		2 interacting genes: HRAS UBQLN2
Entrez ID		25797
HPRD ID		06140
Ensembl ID		ENSG00000115828
Uniprot IDs		Q16769
PDB IDs		1MOI 2AFM 2AFO 2AFS 2AFU 2AFW 2AFX 2AFZ 2ZED 2ZEE 2ZEF 2ZEG 2ZEH 2ZEL 2ZEM 2ZEN 2ZEO 2ZEP 3PBB 3PBE 3SI0 4YU9 4YWY 6GBX 6YI1 6YJY
Enriched GO Terms of Interacting Partners?
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